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E333 · Sequestrants, Stabilisers

Calcium citrates

No known risk

Salt of citric acid, also a calcium source.

Category
Sequestrants, Stabilisers
Vegan
Yes
Vegetarian
Yes

What it is

A salt of citric acid used to regulate tartness and preserve foods by binding to metals.

How it is used in food

Controls acidity, adds a clean tart flavor, and acts as a "sequestrant" (binding trace metals that would otherwise cause fats to spoil).

Commonly found in
  • Soft drinks
  • Processed cheese
  • Jams
  • Desserts

Health and safety

Extremely safe. Citrates are a core component of human cellular energy production (the Krebs cycle).

Evaluated by EFSA and confirmed safe for use in food at authorized levels.

Regulatory status

RegionStatusNotes
Australia & New Zealand
FSANZ
Permitted Permitted under the FSANZ Food Standards Code.
European Union
EFSA / European Commission
Permitted Authorised for food use under EU regulations (Annex II).
United States
FDA (Food and Drug Administration)
Permitted Authorised for food use by the FDA (often GRAS for standard additives).

Identification on labels

E-number
E333

Worth knowing

Sodium citrate is famously used to make nacho cheese sauce incredibly smooth by preventing the cheese proteins from separating when melted.

Conclusion

There is no reason to avoid calcium citrates in your food. As a salt of citric acid, it participates directly in your cells' natural Krebs cycle energy process and provides calcium. EFSA supports its safety for regulating tartness and preserving products like soft drinks, desserts, and processed cheese.

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Entry last reviewed 2026-07-28.

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