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E516 · Sequestrants, Stabilisers

Calcium sulphate

No known risk

Gypsum — tofu coagulant, flour treatment.

Category
Sequestrants, Stabilisers
Vegan
Yes
Vegetarian
Yes

What it is

A chloride or sulphate mineral salt used as a firming agent, flavor enhancer, or salt substitute.

How it is used in food

A popular coagulant for making Chinese-style tofu, resulting in a tender texture.

Commonly found in
  • Canned vegetables
  • Cheese making
  • Brewing water
  • Low-sodium salt

Health and safety

None at the levels used. It is barely soluble, so most of what is added passes through unabsorbed.

No safety concern identified; permitted at quantum satis.

Regulatory status

RegionStatusNotes
Australia & New Zealand
FSANZ
Permitted Permitted under the FSANZ Food Standards Code.
European Union
EFSA / European Commission
Permitted Authorised for food use under EU regulations (Annex II).
United States
FDA (Food and Drug Administration)
Permitted Authorised for food use by the FDA (often GRAS for standard additives).

Identification on labels

E-number
E516

Also printed asCalcium sulfate

Worth knowing

In its natural mineral form, it is known as gypsum, which is used to make drywall.

Conclusion

There is no reason to avoid calcium sulphate in your food. It is a traditional coagulant for tender Chinese-style tofu that is barely soluble in the digestive system, meaning most of it passes through unabsorbed. EFSA has identified no safety concern and permits its use at quantum satis.

References

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Entry last reviewed 2026-07-28.

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