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E217 · Preservatives

Sodium propyl para-hydroxybenzoate

High risk endocrinepreservative

Not authorised in EU and US, but permitted in AU-NZ. No evidence of harm at dietary intake.

Category
Preservatives
Vegan
Yes
Vegetarian
Yes

What it is

Sodium propyl para-hydroxybenzoate is the water-soluble salt of propylparaben, removed from EU food use in 2006.

How it is used in food

Dissolves in water, which plain propylparaben does not — useful in drinks and syrups.

Commonly found in
  • Liquid dietary supplements
  • Confectionery
  • Cured meats
  • Flavouring syrups

Health and safety

It behaves as propylparaben once dissolved, and was withdrawn for the same reason: EFSA could not set an acceptable daily intake after young-rat studies showed effects on sex hormones and the male reproductive organs.

Parabens are highly controversial due to their ability to mimic estrogen in the human body. This has raised concerns about their potential to disrupt the endocrine system and affect reproductive health.

Suspected endocrine disruptor

general population · evidence: suspected

Parabens are known xenoestrogens that can mimic estrogen in the body, raising concerns about long-term hormonal disruption.

EFSA re-evaluation of parabens

Removed from the EU list of permitted food additives in 2006 alongside E216.

Regulatory status

RegionStatusNotes
Australia & New Zealand
FSANZ
Permitted Permitted.
European Union
EFSA / European Commission
Not approved Not on the EU authorised list of food additives (Annex II).
United States
FDA (Food and Drug Administration)
Not approved Not permitted in US food. The US listings cover methylparaben (21 CFR 184.1490) and propylparaben (184.1670) as the free esters; the sodium salts appear in neither 21 CFR nor FDA's Substances Added to Food inventory.

Identification on labels

E-number
E217

Alternatives to this additive

How it is made

Made by neutralising propylparaben with sodium hydroxide.

  1. Esterification — p-Hydroxybenzoic acid is reacted with an alcohol in the presence of a catalyst.

Worth knowing

The sodium salt exists purely for solubility; in the body it is the same molecule as E216.

Conclusion

Due to its longer propyl chain, EFSA concluded in 2004 that it exhibited stronger endocrine disrupting effects than shorter parabens, and it was subsequently banned from food use in the EU.

References

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Entry last reviewed 2026-07-28.

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