ScanWise
E641 · Flavour enhancers

Leucine

No known risk

A safe and naturally occurring essential amino acid.

Category
Flavour enhancers
Vegan
Yes
Vegetarian
Yes

What it is

An essential amino acid sometimes used as a flavor modifier or tableting lubricant.

How it is used in food

An essential branched-chain amino acid used as a flavor modifier and processing aid; nutritionally, leucine is a key trigger of muscle protein synthesis.

Commonly found in
  • Food supplements
  • Sweeteners

Health and safety

Completely safe; it is an essential dietary amino acid.

As an essential amino acid consumed in gram quantities daily from ordinary protein foods, leucine has no relevant toxicity at additive levels. It also appears in pharmaceutical tabletting as a safe excipient.

Regulatory status

RegionStatusNotes
Australia & New Zealand
FSANZ
Permitted Permitted under the FSANZ Food Standards Code.
European Union
EFSA / European Commission
Permitted Authorised for food use under EU regulations (Annex II).
United States
FDA (Food and Drug Administration)
Permitted Authorised for food use by the FDA (often GRAS for standard additives).

Identification on labels

E-number
E641

Worth knowing

Leucine is the same amino acid bodybuilders seek in whey protein and BCAA supplements — the amounts used as a food additive are trivial compared with normal dietary intake.

Conclusion

A safe and naturally occurring essential amino acid.

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Entry last reviewed 2026-07-28.

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